Types of DNA Repair Mechanisms MCQ




DNA repair mechanisms in cells include base excision repair (BER), nucleotide excision repair (NER), mismatch repair (MMR), homologous recombination (HR), and non-homologous end joining (NHEJ). These pathways correct various types of DNA damage, ensuring genomic stability and preventing mutations that can lead to diseases like cancer. This article on “DNA Repair Quiz” will help you to understand the different pathways of DNA repair mechanisms in the cells.

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1. 
DNA repair mechanisms are crucial for maintaining the integrity of the genome by fixing various types of DNA damage. Which of the following is NOT a common type of DNA damage repaired by these mechanisms?

2. 
Which DNA repair mechanism is specifically involved in repairing thymine dimers caused by UV radiation?

3. 
The repair mechanism that fixes DNA damage by removing and replacing a damaged nucleotide along with a few adjacent bases is called:

4. 
Mutations in genes involved in DNA repair can lead to increased susceptibility to cancer and other diseases. The hereditary condition known as xeroderma pigmentosum is caused by defects in which DNA repair pathway?

5. 
The DNA repair mechanism that primarily acts during the S phase of the cell cycle to fix errors introduced during DNA replication is called:

6. 
The repair mechanism that involves the use of a complementary DNA strand to fill in the gap left by damaged DNA is called:

7. 
Double-strand breaks in DNA can be repaired by two main mechanisms: non-homologous end joining (NHEJ) and:

8. 
The enzyme responsible for removing damaged bases during base excision repair (BER) is called:

9. 
Which DNA repair mechanism is considered an error-prone process and may lead to mutations in the repaired DNA?

10. 
The repair mechanism known as nucleotide excision repair (NER) is particularly important for repairing DNA damage caused by:

11. 
In nucleotide excision repair (NER), damaged bases are excised and removed as part of a larger oligonucleotide. The gap is then filled by:

12. 
Which DNA repair mechanism involves the use of specialized proteins to recognize and bind to DNA lesions, initiating the repair process?

13. 
The repair mechanism non-homologous end joining (NHEJ) is particularly important for fixing:

14. 
Which DNA repair mechanism specifically targets mismatches that occur during DNA replication and corrects them?

15. 
In humans, mutations in DNA repair genes can lead to a condition called hereditary non-polyposis colorectal cancer (HNPCC), which is associated with defects in:

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