MCQ on Nucleosome Model of Chromosome




A nucleosome is the basic unit of DNA packaging in eukaryotes. It consists of a segment of DNA wrapped around a core of histone proteins. Nucleosomes help condense and organize DNA, regulating access for processes like transcription and DNA replication. This is an MCQ on Nucleosome Model and Organization of DNA in the Nucleosome.

Learn more: Nucleosome Model of Chromosomes Short Notes



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1. 
What are nucleosomes?

2. 
What is the fundamental structural unit of a nucleosome?

3. 
Which protein family is responsible for binding to DNA and forming nucleosomes?

4. 
How many types histone proteins are in an octamer core of a nucleosome?

5. 
What is the charge of histone proteins, which allows them to interact with the negatively charged DNA?

6. 
Which of the following histone proteins is not part of the histone octamer in a nucleosome?

7. 
What is the role of the linker DNA in a nucleosome?

8. 
Which of the following is true about the "beads on a string" model of chromatin structure?

9. 
How does acetylation of histones affect nucleosome structure and gene expression?

10. 
Which enzyme is responsible for adding acetyl groups to histones?

11. 
What is the function of histone deacetylases (HDACs) in chromatin remodeling?

12. 
Which type of DNA sequences are preferred by nucleosomes for binding?

13. 
What is the role of nucleosomes in regulating access to DNA during processes like transcription and replication?

14. 
What is the purpose of chromatin remodeling complexes in the cell?

15. 
In what form is DNA more accessible for gene expression and other cellular processes?

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MCQ on Nucleosome Model




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