MCQ on G Protein-Coupled Receptors (GPCRs)




GPCR, or G protein-coupled receptor, is a cell membrane protein that detects external signals and activates intracellular responses. It plays a crucial role in cell communication, mediating processes such as neurotransmission, immune response, and hormonal regulation in various physiological functions. This is an MCQ on G Protein-Coupled Receptors (GPCRs).

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1. 
What is the full name of the acronym "GPCR" in the context of cell biology?

2. 
Which of the following is NOT a common function of GPCRs in cells?

3. 
When a ligand binds to a GPCR, it triggers a conformational change that activates the associated:

4. 
The activation of GPCRs leads to the exchange of GDP for GTP on the G-protein. What role does GTP play in this process?

5. 
The rhodopsin receptor is a GPCR involved in which sensory function?

6. 
In GPCR signaling, what type of cellular response can be mediated by the activation of adenylyl cyclase?

7. 
GPCR signaling can lead to the activation of different intracellular pathways. Which of the following pathways involves the activation of phospholipase C (PLC) and the production of inositol triphosphate (IP3)?

8. 
In GPCR signaling, which subunit of the G-protein carries the GTP and activates downstream effectors?

9. 
GPCR signaling is essential for the body's response to various stimuli. Which of the following is NOT a physiological process regulated by GPCRs?

10. 
What is the significance of GPCRs in drug development and pharmacology?

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MCQ on G Protein-Coupled Receptors (GPCRs)






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