What is Ecological Succession? Definition: Ecological succession is the gradual and sequential replacement of one community by the other in an area over a period of time. According to E.P. Odum (1971), the ecological succession is an orderly process of community change in a unit area. It is the process […]
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Tumor Suppressor Gene Rb and its Role in Cell Cycle and Cancer
What is Retinoblastoma? Retinoblastoma or RB is a type of cancer affecting the retina of young individuals. RB occurs in the human population both spontaneously and as a heritable disorder. The genetic reason for the occurrence of RB is associated with a structural aberration of the chromosome. In human, the […]
Continue ReadingExtrinsic Pathway of Apoptosis (Apoptosis Molecular Mechanism Part 2)
Extrinsic Pathway of Apoptosis (The Receptor-Mediated Programmed Cell Death Pathway) In the extrinsic pathway of apoptosis, the death-inducing signal for the programmed cell death is triggered by an external stimulus. For receiving such an external death-inducing signal, the cell possesses plasma membrane receptors specific to each stimulus and thus the […]
Continue ReadingIntrinsic Pathway of Apoptosis (Apoptosis Molecular Mechanism Part 1)
Two Types of Apoptosis In the previous post, we have discussed the characteristic features and significance of programmed cell death or apoptosis. As we discussed, the stimuli for the execution of programmed cell death can be of internal or external to the apoptotic cell. Based on the source of stimuli, […]
Continue ReadingApoptosis: The Molecular Mechanism of Programmed Cell Death (Short Notes)
What is Apoptosis? Why apoptosis is known as the ‘Programmed Cell Death’? The total number of cells in an organ or organism is fundamentally fixed to a specific range in all multicellular organisms. In every multi-cellular organism, the cell number is effectively controlled by two strategies- (a) by regulating cell […]
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