MCQ on Purine and Pyrimidine




Purine and pyrimidine are two types of nitrogenous organic compounds. Purines, like adenine and guanine, have a double-ring structure and are found in DNA, RNA, and various cellular processes. Pyrimidines, including cytosine, thymine, and uracil, possess a single-ring structure and play a vital role in nucleic acids, such as DNA and RNA. This is an MCQ on Purine and Pyrimidine Structure and Functions.

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1. 
Which class of organic compounds includes both purines and pyrimidines?

2. 
Which of the following are purine bases found in DNA?

3. 
How many carbon atoms are present in the purine ring?

4. 
In RNA, which base pairs with adenine?

5. 
Which of the following is a pyrimidine-containing nucleotide?

6. 
What type of bond connects the pyrimidine and purine base pairs in DNA and RNA?

7. 
Which genetic disorder is characterized by the inability to properly metabolize uracil, leading to a buildup of toxic substances?

8. 
What is the primary function of the enzyme thymidylate synthase in pyrimidine metabolism?

9. 
Which of the following is a pyrimidine base found in nucleic acids?

10. 
Which pyrimidine base is specific to DNA and not found in RNA?

11. 
In pyrimidine metabolism, which enzyme catalyzes the conversion of orotate to UMP (uridine monophosphate)?

12. 
What is the primary function of the enzyme dihydroorotate dehydrogenase in pyrimidine metabolism?

13. 
What is the end product of the breakdown of adenine in purine metabolism?

14. 
In purine metabolism, which enzyme is responsible for the conversion of guanine to xanthine?

15. 
Which genetic disorder is characterized by the accumulation of uric acid due to a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT)?

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