MCQ on Histone: Organization and Functions




Histone proteins are highly alkaline proteins found in eukaryotic cell nuclei. They form the core around which DNA wraps to form nucleosomes, the basic units of chromatin. Histones play crucial roles in DNA packaging, gene regulation, and epigenetic modifications, influencing gene expression and cellular processes within the nucleus. This is an MCQ on Histone Proteins: Structure and Functions.

|  Cell and Molecular Biology Notes  |  Cell and Molecular Biology PPT  |



1. 
Histones are a family of proteins primarily associated with:

2. 
Which of the following is NOT a major class of histone proteins found in eukaryotes?

3. 
Histones have a positive charge due to their high content of which amino acid?

4. 
The DNA double helix is wrapped around histone octamers to form a structure known as a:

5. 
Histones play a critical role in regulating gene expression. When histones are tightly packed with DNA, what is the effect on gene transcription?

6. 
The addition of acetyl groups to histone proteins is associated with:

7. 
Which enzyme is responsible for adding acetyl groups to histone proteins, leading to chromatin relaxation and increased gene transcription?

8. 
Histone modifications, such as methylation and acetylation, can be heritable, meaning they can be passed on to daughter cells during cell division. This phenomenon is known as:

9. 
The "histone code" refers to:

10. 
Which histone modification is associated with gene silencing and condensation of chromatin?

11. 
Histones serve as binding sites for various regulatory proteins, including those involved in DNA repair, replication, and transcription. What is the collective term for these regulatory proteins?

12. 
In eukaryotes, the "beads on a string" structure represents:

13. 
Histone modifications can be reversed by enzymes that remove acetyl or methyl groups from histones. What are these enzymes called?

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