MCQ on Lipopolysaccharides (LPS)




Lipopolysaccharide (LPS) is a vital component of gram-negative bacterial outer membranes. Comprising lipid A, O-antigen, and core polysaccharide, LPS influences bacterial integrity, immune responses, and pathogenicity. Its structural variations contribute to diverse functions, making it a key biomolecule in host-microbe interactions. This is an MCQ on Lipopolysaccharides (LPS) Structure and Functions.

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1. 
In which type of bacteria are lipopolysaccharides (LPS) primarily found?

2. 
Which component of lipopolysaccharides (LPS) can induce a strong immune response and trigger inflammation in the host?

3. 
The O-antigen, also known as the O-polysaccharide, is the variable outermost region of LPS. It plays a role in:

4. 
What is the role of the core polysaccharide in lipopolysaccharides (LPS)?

5. 
Which region of LPS is responsible for the unique properties of Gram-negative bacterial outer membranes, such as their impermeability to many substances?

6. 
Lipopolysaccharides (LPS) are known to be potent endotoxins. In high amounts, LPS can lead to a condition called:

7. 
How does the O-antigen in LPS contribute to bacterial antigenic diversity and immune evasion?

8. 
What is the function of lipopolysaccharides (LPS) in the Gram-negative bacterial cell envelope?

9. 
Which component of LPS anchors it to the outer membrane of Gram-negative bacteria?

10. 
What is the significance of the "endotoxin" property of LPS in the context of bacterial infections?

11. 
LPS is often used as a target for antibiotic development. Which of the following statements about antibiotics targeting LPS is true?

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MCQ on Lipopolysaccharides






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