Cancer is a disease of the genome. And that’s what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should’ve stopped, and that’s cancer. And those mistakes are mistakes of DNA. Francis Collins What is Base Excision Repair or BER? […]
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easybiologyclass tutorials in biochemistry
Photoreactivation : Method of DNA Repair for the Recovery of UV Induced DNA Damages by Phytolyase Enzyme and Visible Light
Science is beautiful when it makes simple explanations of phenomena or connections between different observations. Stephen W. Hawking, 2011 What is Photoreactivation? Photoreactivation is a type of DNA repair mechanism present in prokaryotes, archaea and in many eukaryotes. It is the recovery of ultraviolet irradiated damages of DNA by visible […]
Continue ReadingDNA Repair Mechanism – Part I Introduction (DNA Damaging Agents, DNA Damages and Recovery of DNA Damages)
“Genetic variation is important for evolution, but the survival of the individuals demand genetic stability” DNA is the genetic information carrier molecule in the cell and thus it is very essential to keep the genetic information intact. Even though DNA holds a prime position, it is one of the highly […]
Continue ReadingArtemisinin: A Wonder Phyto-drug Against Malarial Parasite: Plasmodium falciparum; & Nobel Prize Winning Contribution of Prof. Youyou Tu, China (Nobel Prize 2015: Physiology and Medicine)
. Artemisinin is an anti-malarial parasite drug extracted from a Chinese medicinal plant called sweet wormwood (Artemisia annua; Asteraceae family). It is also known as qinghaosu in Chinese and it is the most rapid acting drug currently available against the malarial parasite, Plasmodium falciparum. The 2015 Nobel Prize in Physiology […]
Continue ReadingNucleotide Biosynthesis (De-novo & Salvage Synthesis of Purine & Pyrimidine Nucleotides in the Cells)
“The formation of DNA’s structure by Watson and Crick may turn out to be the greatest developments in the field of molecular genetics in recent years” Linus Pauling, 1953 Purines (Adenine & Guanine) and pyrimidines (Thymine, Cytosine & Uracil) are the two classes of nucleotides which forms the nucleic acids (DNA […]
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