Lecture notes in Microbiology

Difference between Murein and Pseudomurein- A Comparison Table

difference murein and pseudomurein

Murein vs Pseudomurein – A Comparison Table
(Similarities and Difference between Peptidoglycan and Pseudopeptidoglycan)

The majority of Bacteria and Archaebacteria have a rigid cell wall around its plasma membrane. The peptidoglycan (also called murein) cell wall, which is considered as the biomarker of bacteria, is absent in the cell wall of Archaea. However, the members of Archaea show great diversity in their cell wall composition. The cell wall in Archaea may contain polysaccharides, proteins or glycoproteins. Some methanogenic Archaebacteria possess a cell wall molecule that is remarkably similar to that of the peptidoglycan molecules in the cell wall of bacteria. These cell wall molecules are called Pseudopeptidoglycan or Pseudomurein. The peptidoglycan and pseudopeptidoglycan shows many structural and functional similarities and differences. The present post describes the Similarities and Differences between the Peptidoglycan (Murein) and Pseudopeptidoglycan (Pseudomurein) with a comparison table.

Similarities between Peptidoglycan (Murein) and Pseudopeptidoglycan (Pseudomurein)

Ø. Both Peptidoglycan and Pseudopeptidoglycan are glycoconjugates.

Ø. Both are polymers of monomer units joined by specific glycosidic bonds.

Ø. Both are hetero-polysaccharides (consists of more than one type of monomer units).

Ø. Both contain long un-branched carbohydrate chains inter-connected by short peptide segments.

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