Biotechnology Lecture Notes

Batch Fermentation vs Continuous Fermentation Process: Similarities and Differences – A Comparison Table


Difference continuous and batch fermentation

Batch Fermentation vs Continuous Fermentation Process
(Similarities and difference between Batch Fermentation and Continuous Fermentation Process)

Batch Fermentation and Continuous Fermentation are the two commonly adopted Industrial Fermentation methods for the scale production of microbial biomass or metabolites.

Batch Fermentation: Here the fermenter is first filled with the raw material (carbon source). Then the microbes are added and allowed to ferment the raw material under optimum pH and aeration. The products remain in the fermenter until the completion of fermentation. After fermentation, the products are extracted and the fermenter is cleaned and sterilized before next round. Thus here the fermentation is done as separate batches.

Continuous Fermentation: Here the exponential growth rate of the microbes is maintained in the fermenter for prolonged periods of time in by the addition of fresh media are regular intervals. The metabolite or the product of fermentation is extracted for the overflow from the fermenter. Thus unlike batch fermentation, in continuous fermentation, the fermentation process never stops in between and it continues to run for a long period of time with the addition of nutrients and harvesting the metabolites at regular intervals.

The present post describes the Similarities and Differences between Batch Fermentation and Continuous Fermentation Process as a Comparison Table.

Similarities between Batch Culture and Continuous Culture Fermentation Methods

Ø  Both are industrial fermentation methods for the large scale production.

Ø  Both methods can be used for the production of microbial biomass or products.

Ø  Both run under controlled environmental conditions

Ø  The mechanical components of fermenter is almost similar in both types




Difference between Batch Fermentation and Continuous Fermentation Process

Continue reading

Biotechnology Lecture Notes

Industrial Fermentation Process (Batch, Fed-batch and Continuous Fermentation)


types of fermentation process

Fermentation Technology
(Types of Industrial Fermentation Processes)

Fermentation: An art from the past, a skill for the future…
Brain McNeil

What is fermentation?

Ø  Fermentation is a metabolic process which converts carbohydrates to alcohols, organic acids or gases by the activity of enzymes of microbial origin.

Ø   Microbes involved in fermentation process: Bacteria and Fungi.

Ø  The process of anaerobic respiration in the muscle cells of animals during exercise which produce lactic acid is also a type of fermentation.

Ø  The technique of fermentation was very ancient in origin.

Ø  Egyptians and Sumerians had the knowledge of the technique of converting starchy grains to alcoholics.

Ø  For a microbiologist, the word ‘fermentation’ means many processes such as:

$   A method of mass cultivation of microbes under aerobic or anaerobic conditions.

$   Any biological process occurs in the absence of oxygen.

$   Spoilage of food by microbial activity.

$   Production of alcoholic beverages, organic acids, antibiotics or biopolymers

$   Partial oxidation of carbohydrates

What is industrial fermentation?

Ø  The intentional use of fermentation technology for the large scale production of microbial biomass or metabolites is called industrial fermentation.

Continue reading