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Computational Biology and Bioinformatics Ph.D. Entrance Test Question Paper 2015 (Kerala University)


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KERALA UNIVERSITY Ph.D. ENTRANCE EXAMINATION
OCTOBER- 2015
FACULTY OF APPLIED SCIENCES

COMPUTATIONAL BIOLOGY AND BIOINFORMATICS

Time: 140 Minutes                                                  Maximum Marks: 160

Note: Answer any twelve questions from Section B and one question from Section C in the subject concerned. In Section B, each question carries 10 marks. Section C carries 40 marks. In Section B an answer should not exceed 100 words. In Section C, an answer should not exceed 500 words.

SECTION – B

(1). Explain the terms:

a.  Sequence Similarity and Sequence Identity

b.  E-value in BLAST

(2). Align the following sequence using dynamic programming for Global alignment: ATTGC and AGGC

(3). Compare the following sequence alignment tools:

a. PSI-BLAST

b. FASTA

(4). What is meant by Consensus sequences in Bioinformatics? Compare Sequence logo and Consensus logo.

(5). Explain the Multiple Sequence Alignment algorithm of ClustalW.

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