Blood Plasma vs Blood Serum
(Similarities and Differences between Blood Serum and Plasma)
Blood is a body fluid composed of blood cells suspended in the blood plasma. Blood facilitate the transport of oxygen, carbon dioxide, nutrients and hormones in the body. The terms ‘Blood Plasma’ and ‘Blood Serum’ are synonymously used. In fact, they are two different components of the blood. The blood chiefly composed of three main components; they are serum, plasma and blood corpuscles (RBC and WBC).
Serum: Serum is the liquid part of blood (plasma) without the clotting factors (fibrinogen). Serum = plasma – clotting factors
Plasma: Plasma is the medium of blood in which the blood cells (RBC and WBC) and other components of the blood are suspended. The plasma composed of serum and clotting factor.
The present post discuss the Similarities and Differences between Blood Serum and Plasma
Similarities between Serum and Plasma
Ø Both serum and plasma are the components of blood.
Ø Both serum and plasma are used for blood testing for diagnostic purpose.
Ø Both are the fluid component of blood.
Ø The composition plasma and serum is more or less similar.
Ø Both contain hormones, glucose and electrolytes.
Ø Both contain antigens and antibodies.
Difference between Serum and Plasma
|Sl. No.||Blood Serum||Blood Plasma|
|1||Definition: Serum is the liquid part of the blood (plasma) without the clotting factor (fibrinogen)||Definition: Plasma is the medium of blood in which the blood cells (RBC and WBC) and other components are suspended|
|2||Serum do not contain blood cells||Blood cells are suspended in the blood plasma|
|3||Serum do not contain fibrinogen (the clotting factor)||Plasma contain fibrinogen|
|4||Blood serum is released from the blood clot||Blood plasma is the fluid part of the unclotted blood|
|5||Serum is a clear fluid||Plasma is a faint yellow fluid|
|6||The volume of serum is comparatively lesser than blood plasma||The volume of blood plasma is more than that of serum. Plasma constitute about 55% of the total volume of blood|
|7||Water content of serum is 90%||Water content of plasma is 92 – 95%|
|8||Blood serum cannot clot||Blood plasma can clot|
|9||Serum is obtained by the centrifugation of coagulated blood||Plasma is obtained by the centrifugation of blood added with any anticoagulant|
|10||Comparatively shorter shelf life in storing||Higher shelf life in storage, the plasma can be stored even for 10 years with suitable methods|
|11||Serum is the important source of blood electrolytes||Plasma is the main medium of excretory product circulation through the blood|
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